How Does Nandrolone Interfere with Testosterone Production?
Popular Anabolic Steroid-Nandrolone.
Nandrolone decanoate, a popular anabolic steroid with athletes and young adults trying to improve their appearance.
Many steroid users take 600 to 5,000 milligrams per week. That is 10 to 1,000 times greater than the normal testosterone production in testes. At the University of Foggia in Italy, research found that nandrolone suppressed testosterone production in isolated Leydig cells of the testes. The effects were dose dependent. Meaning higher doses suppressed production most. Testosterone, controlled by a feedback mechanism between the gypothalamus, pituitary and testes.
Steroids suppress donadotropin-releasing factor in the hypothalamus. Also the luteinizing hormone and follicle-stimulating hormone in the pituitary. Testicular suppression leads to reduced natural testosterone made. Also suppressed sperm production and reduced testicular weight. The typical steroid user in America is a 30-year old, fit non-athlete with a normal job. Also, taking the steroids to get stronger and look better. Many are married hoping to start a family. Steroids make this more difficult. Furthermore, use muscle supplements that contain no banned substances. While these products will not effect the making of testosterone.